Refrigerants, Naturally! (RN) is a global initiative of companies committed to combat climate change and ozone layer depletion by substituting harmful fluorinated gases ("F-gases", such as CFCs, HCFCs and HFCs) with natural refrigerants with a focus on their point-of-sale cooling applications. Point-of-sale cooling may include the entire retail infrastructure, e.g. HVAC, but excludes manufacturing and distribution. Refrigerants, Naturally! is supported by Greenpeace and the United Nation Environment Programme and recognised as a "Partnership for Sustainable Development" by the UN Commission on Sustainable Development.

Key goals of the initiative are to

• Promote a shift in the point-of-sale cooling technology towards natural refrigerants with a low-or non-Global Warming Potential and a zero Ozone Depleting Potential and that is safe, reliable and cost effective,
• Do this whilst improving or (at least) equaling energy efficiency compared to existing fluorocarbon based technology,
• Provide a platform and a critical mass in communicating with the refrigeration technology supply chain, with other users, governments and civil society.

Each member company is required to

• Publicly commit to the objectives of the initiative,
• Develop prospective timetables to move their operation towards these goals and periodically share their progress with members,
• Make a substantial effort or investment to progressively replace fluorocarbons with natural refrigerants. This may include R&D, testing, financial investment, staff time or public engagement,
• Share technical information about alternative refrigeration between the partners of the initiative via regular meetings, special events/workshops, and bilateral exchanges,
• Share data and results with external stakeholders, such as their wider supply chain, their industry peer groups, government decision makers, and the public.